Novo Nordisk has entered into separate research collaborations with Omega and Cellarity. The Omega collaboration will leverage its proprietary platform technology to develop an epigenomic controller designed to enhance metabolic activity. The Cellarity collaboration aims to unravel novel biological drivers of MASH.
The Omega collaboration will leverage its proprietary platform technology to develop an epigenomic controller designed to enhance metabolic activity as a part of a potential new treatment approach for obesity management. The Cellarity collaboration aims to unravel novel biological drivers of MASH and will leverage Cellarity’s platform to develop a small molecule therapy against this disease.
“This is an important moment in our partnership with Flagship Pioneering. We look forward to advancing these research programmes with Omega and Cellarity in the coming years as we explore bold new treatment strategies with the potential to make a significant impact for people living with obesity or MASH,” said Marcus Schindler, EVP and chief scientific officer at Novo Nordisk.
“Precision epigenomic control is an emerging approach to medicine that allows us to pre-transcriptionally modulate gene expression with an unparalleled level of specificity,” said Mahesh Karande, president and CEO of Omega Therapeutics. “By leveraging Novo Nordisk’s deep expertise in the space and our OMEGA platform, we have the opportunity to tap into the body’s natural processes that control metabolic activity and potentially develop an alternative, more durable approach to obesity management.”
“Cellarity is developing a new paradigm in drug creation by harnessing the power of AI and multiomics data,” said Fabrice Chouraqui, Pharm.D., CEO of Cellarity and a CEO-partner at Flagship Pioneering. “Our partnership with Novo Nordisk, the world leader in metabolic disease, creates a unique opportunity for application of our platform to identify novel vantage points into the progression of MASH and develop a transformative small molecule therapy against this debilitating disease.”
“These collaboration agreements with Omega and Cellarity are an exciting demonstration of how our partnership with Novo Nordisk is leveraging the unique bioplatform technologies within the Flagship ecosystem to develop potentially transformational medicines,” said Paul Biondi, president, Pioneering Medicines, and executive partner, Flagship Pioneering. “By bringing these innovative platforms together with Novo Nordisk’s deep expertise in cardiometabolic disease we have incredible potential to make a bigger leap forward for patients.”
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